A brief history of RNAi: the silence of the genes.

نویسندگان

  • George L Sen
  • Helen M Blau
چکیده

The use of the RNA interference (RNAi) pathway to eliminate gene products has greatly facilitated the understanding of gene function. Behind this remarkable pathway is an intricate network of proteins that ensures the degradation of the target mRNA. In this review, we explore the history of RNAi as well as highlighting recent discoveries.

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عنوان ژورنال:
  • FASEB journal : official publication of the Federation of American Societies for Experimental Biology

دوره 20 9  شماره 

صفحات  -

تاریخ انتشار 2006